Please see Important Safety Information,
including warning about heart failure, below.

For many adults with type 2 diabetes I'm getting the power of
2 medicines in 1 tablet to
help manage my blood sugar
Individual results may vary.
Available as a GENERIC

OSENI Is Available as a Generic

With the same medicines and formulation as brand name OSENI, this is the only DPP-4i and pioglitazone combination available in generic form.

Ask your doctor or pharmacist how you can save with either the brand or generic option as coverage may vary.

Important Safety Information

WARNING: RISK OF HEART FAILURE

OSENI (alogliptin and pioglitazone) can cause heart failure and cause your body to keep extra fluid (fluid retention), which leads to swelling (edema) and weight gain. Extra body fluid can make some heart problems worse or lead to heart failure. Before you start taking OSENI, tell your doctor if you have ever had heart failure or have problems with your kidneys. Call your doctor right away if you experience shortness of breath or trouble breathing (especially when you lie down), an unusually fast increase in weight or swelling or fluid retention (especially in the feet, ankles or legs). These may be symptoms of heart failure.

OSENI may not be right for everyone. OSENI can cause serious side effects.

Do not take OSENI if you are allergic to any of its ingredients.

Stop taking OSENI and contact your doctor or go to the nearest hospital emergency room right away if you experience swelling of your face, lips, throat, or other areas on your skin, difficulty swallowing or breathing, raised red areas on your skin (hives), skin rash, itching, flaking, or peeling, as these may be symptoms of a serious allergic reaction.

Inflammation of the pancreas (pancreatitis), which may be severe, can happen to people taking OSENI. Tell your doctor if you have ever had pancreatitis, kidney problems, or liver problems. Stop taking OSENI and call your doctor right away if you have pain in your stomach area (abdomen) that is severe and will not go away. The pain may be felt going from your abdomen through to your back. The pain may happen with or without vomiting. These may be symptoms of pancreatitis.

OSENI may cause liver problems. Call your doctor right away if you experience nausea, vomiting, stomach pain, unusual or unexplained tiredness, loss of appetite, dark urine, or yellowing of your skin or eyes.

Women are at a higher risk of having broken bones (fractures) while taking OSENI.

There may be an increased chance of having bladder cancer when you take OSENI. You should not take OSENI if you are receiving treatment for bladder cancer. Tell your doctor right away if you have blood or a red color in your urine, an increased need to urinate, or pain while you urinate as these may be symptoms of bladder cancer.

If you take OSENI with another medicine that can cause low blood sugar, such as a sulfonylurea or insulin, your risk of getting low blood sugar is higher. The dose of your sulfonylurea medicine or insulin may need to be lowered while you take OSENI. If you have symptoms of low blood sugar, you should check your blood sugar and treat if low, and then call your doctor. Signs and symptoms of low blood sugar include shaking or feeling jittery, sweating, fast heartbeat, change in vision, hunger, headache, change in mood, confusion, or dizziness.

Tell your doctor right away if you have any changes in your vision. Your doctor should check your eyes regularly.

If you are a woman of childbearing age, but do not have monthly periods, talk to your doctor before taking OSENI, as it could increase your chance of becoming pregnant.

Some people who take medicines called DPP-4 inhibitors, one of the medicines in OSENI, may develop joint pain that can be severe. Call your doctor if you have severe joint pain.

Before taking OSENI, you should tell your doctor if you are pregnant, planning to become pregnant, breastfeeding, or planning to breastfeed. It is not known if OSENI can harm an unborn baby, or if it passes into breast milk.

The most common side effects of OSENI were stuffy or runny nose and sore throat (4.9%), back pain (4.2%), and cold-like symptoms (upper respiratory tract infection; 4.1%).

Tell your doctor about all the medicines, vitamins, and supplements you take. Medicines can affect each other. You should contact your doctor before you start or stop other medicines. You may need to have your dose of OSENI, or certain other medicines, changed.

Talk to your doctor or healthcare professional. Please see full Prescribing Information, including Medication Guide for OSENI (alogliptin and pioglitazone).

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Indication for OSENI

OSENI is a prescription medicine used with diet and exercise to improve blood sugar (glucose) control in adults with type 2 diabetes. OSENI is not for patients with type 1 diabetes or diabetic ketoacidosis (increased ketones in blood or urine).

Indication for OSENI (alogliptin and pioglitazone) 25 mg/15 mg, 25 mg/30 mg, and 25 mg/45 mg Tablets

OSENI is a prescription medicine used with diet and exercise to improve blood sugar (glucose) control in adults with type 2 diabetes. OSENI is not for patients with type 1 diabetes or diabetic ketoacidosis (increased ketones in blood or urine).

*Eligibility Restrictions Apply: This offer cannot be used if you are a beneficiary of, or any part of your prescription is covered by: (1) any federal or state healthcare program (Medicare, Medicaid, TRICARE, etc) including a state pharmaceutical assistance program, (2) the Medicare Prescription Drug Program (Part D), or if you are currently in the coverage gap, or (3) insurance that is paying the entire cost of the prescription. Save up to $100 on OSENI and up to $10 on metformin each month when your prescriptions are filled at the same time. Depending on insurance coverage, savings and
co-pay may vary. Savings card cannot be used with generic of OSENI.

Important Safety Information

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Tap Here for Important Safety Information

Important Safety Information

WARNING: RISK OF HEART FAILURE

OSENI (alogliptin and pioglitazone) can cause heart failure and cause your body to keep extra fluid (fluid retention), which leads to swelling (edema) and weight gain. Extra body fluid can make some heart problems worse or lead to heart failure. Before you start taking OSENI, tell your doctor if you have ever had heart failure or have problems with your kidneys. Call your doctor right away if you experience shortness of breath or trouble breathing (especially when you lie down), an unusually fast increase in weight or swelling or fluid retention (especially in the feet, ankles or legs). These may be symptoms of heart failure.

OSENI may not be right for everyone. OSENI can cause serious side effects.

Do not take OSENI if you are allergic to any of its ingredients.

Stop taking OSENI and contact your doctor or go to the nearest hospital emergency room right away if you experience swelling of your face, lips, throat, or other areas on your skin, difficulty swallowing or breathing, raised red areas on your skin (hives), skin rash, itching, flaking, or peeling, as these may be symptoms of a serious allergic reaction.

Inflammation of the pancreas (pancreatitis), which may be severe, can happen to people taking OSENI. Tell your doctor if you have ever had pancreatitis, kidney problems, or liver problems. Stop taking OSENI and call your doctor right away if you have pain in your stomach area (abdomen) that is severe and will not go away. The pain may be felt going from your abdomen through to your back. The pain may happen with or without vomiting. These may be symptoms of pancreatitis.

OSENI may cause liver problems. Call your doctor right away if you experience nausea, vomiting, stomach pain, unusual or unexplained tiredness, loss of appetite, dark urine, or yellowing of your skin or eyes.

Women are at a higher risk of having broken bones (fractures) while taking OSENI.

There may be an increased chance of having bladder cancer when you take OSENI. You should not take OSENI if you are receiving treatment for bladder cancer. Tell your doctor right away if you have blood or a red color in your urine, an increased need to urinate, or pain while you urinate as these may be symptoms of bladder cancer.

If you take OSENI with another medicine that can cause low blood sugar, such as a sulfonylurea or insulin, your risk of getting low blood sugar is higher. The dose of your sulfonylurea medicine or insulin may need to be lowered while you take OSENI. If you have symptoms of low blood sugar, you should check your blood sugar and treat if low, and then call your doctor. Signs and symptoms of low blood sugar include shaking or feeling jittery, sweating, fast heartbeat, change in vision, hunger, headache, change in mood, confusion, or dizziness.

Tell your doctor right away if you have any changes in your vision. Your doctor should check your eyes regularly.

If you are a woman of childbearing age, but do not have monthly periods, talk to your doctor before taking OSENI, as it could increase your chance of becoming pregnant.

Some people who take medicines called DPP-4 inhibitors, one of the medicines in OSENI, may develop joint pain that can be severe. Call your doctor if you have severe joint pain.

Before taking OSENI, you should tell your doctor if you are pregnant, planning to become pregnant, breastfeeding, or planning to breastfeed. It is not known if OSENI can harm an unborn baby, or if it passes into breast milk.

The most common side effects of OSENI were stuffy or runny nose and sore throat (4.9%), back pain (4.2%), and cold-like symptoms (upper respiratory tract infection; 4.1%).

Tell your doctor about all the medicines, vitamins, and supplements you take. Medicines can affect each other. You should contact your doctor before you start or stop other medicines. You may need to have your dose of OSENI, or certain other medicines, changed.

Talk to your doctor or healthcare professional. Please see full Prescribing Information, including Medication Guide for OSENI (alogliptin and pioglitazone).

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Indication for OSENI

OSENI is a prescription medicine used with diet and exercise to improve blood sugar (glucose) control in adults with type 2 diabetes. OSENI is not for patients with type 1 diabetes or diabetic ketoacidosis (increased ketones in blood or urine).

Indication for OSENI (alogliptin and pioglitazone) 25 mg/15 mg, 25 mg/30 mg, and 25 mg/45 mg Tablets

OSENI is a prescription medicine used with diet and exercise to improve blood sugar (glucose) control in adults with type 2 diabetes. OSENI is not for patients with type 1 diabetes or diabetic ketoacidosis (increased ketones in blood or urine).

*Eligibility Restrictions Apply: This offer cannot be used if you are a beneficiary of, or any part of your prescription is covered by: (1) any federal or state healthcare program (Medicare, Medicaid, TRICARE, etc) including a state pharmaceutical assistance program, (2) the Medicare Prescription Drug Program (Part D), or if you are currently in the coverage gap, or (3) insurance that is paying the entire cost of the prescription. Save up to $100 on OSENI and up to $10 on metformin each month when your prescriptions are filled at the same time. Depending on insurance coverage, savings and
co-pay may vary. Savings card cannot be used with generic of OSENI.

OSENI Is Now Available as a Generic

With the same medicines and formulation as brand name OSENI, this is the only DPP-4i and pioglitazone combination available in generic form.

Save on your prescription—
ask your doctor or pharmacist if the generic form of OSENI is appropriate for you.